#ifndef MUSCLEFUNCTIONFACTORY_H_ #define MUSCLEFUNCTIONFACTORY_H_ /* -------------------------------------------------------------------------- * * OpenSim: SmoothSegmentedFunctionFactory.h * * -------------------------------------------------------------------------- * * The OpenSim API is a toolkit for musculoskeletal modeling and simulation. * * See http://opensim.stanford.edu and the NOTICE file for more information. * * OpenSim is developed at Stanford University and supported by the US * * National Institutes of Health (U54 GM072970, R24 HD065690) and by DARPA * * through the Warrior Web program. * * * * Copyright (c) 2005-2012 Stanford University and the Authors * * Author(s): Matthew Millard * * * * Licensed under the Apache License, Version 2.0 (the "License"); you may * * not use this file except in compliance with the License. You may obtain a * * copy of the License at http://www.apache.org/licenses/LICENSE-2.0. * * * * Unless required by applicable law or agreed to in writing, software * * distributed under the License is distributed on an "AS IS" BASIS, * * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * * See the License for the specific language governing permissions and * * limitations under the License. * * -------------------------------------------------------------------------- */ /* Update: This is a port of the original code so that it will work with the multibody code RBDL written by Martin Felis. Author: Matthew Millard Date: Nov 2015 */ #include "../geometry/SmoothSegmentedFunction.h" #include "../geometry/SegmentedQuinticBezierToolkit.h" #include #include #include #include /** This is a class that acts as a user friendly wrapper to QuinticBezerCurveSet to build specific kinds of physiologically plausible muscle curves using C2 continuous sets of quintic Bezier curves. This class has been written there did not exist a set of curves describing muscle characteristics that was: 1. Physiologically Accurate 2. Continuous to the second derivative 3. Parameterized in a physically meaningful manner For example, the curves employed by Thelen (Thelen DG(2003). Adjustment of Muscle Mechanics Model Parameters to Simulate Dynamic Contractions in Older Adults. ASME Journal of Biomechanical Engineering (125).) are parameterized in a physically meaningful manner, making them easy to use. However there are many shortcomings of these curves: 1. The tendon and parallel element are not C2 continuous, making them slow to simulate and likely not physiologically accurate. 2. The active force length curve approaches does not achieve its minimum value at a normalized fiber length of 0.5, and 1.5. 3. The force velocity curve is not C2 continuous at the origin. As it is written in the paper the curve is impossible to use with an equilibrium model because it is not invertible. In addition the force-velocity curve actually increases in stiffness as activation drops - a very undesirable property given that many muscles are inactive at any one time. The muscle curves used in the literature until 2012 have been hugely influenced by Thelen's work, and thus similar comments can easily be applied to just about every other musculoskeletal simulation. Another example is from Miller (Miller,RH(2011).Optimal Control of Human Running. PhD Thesis). On pg 149 a physiolgically plausible force velocity curve is specified that gives the user the ability to change the concentric curvature to be consistent with a slow or a fast twitch musle. This curve is not C2 continuous at the origin, but even worse, it contains singularities in its parameter space. Since these parameters do not have a physical interpretation this model is difficult to use without accidentically creating a curve with a singularity. With this motivation I set out to develop a class that could generate muscle characteristic curves with the following properties: 1. Physiologically Accurate 2. Continuous to the second derivative 3. Parameterized in a physically meaningful manner 4. Monotonicity for monotonic curves 5. Computationally efficient These goals were surprisingly time consuming achieve, but these goals have been achieved using sets of C2 continuous quintic Bezier curves. The resulting muscle curve functions in this class take parameters that would be intuitive to biomechanists who simulate human musculoskeletal systems, and returns a SmoothSegmentedFunction which is capable of evaluating the value, and derivatives of the desired function (or actually relation as the case may be). Each curve is made up of one or more C2 quintic Bezier curves x(u), and y(u), with linearily extrapolated ends as shown in the figure below. These quintic curves span 2 points, and achieve the desired derivative at its end points. The degree of curviness can be varied from 0 to 1 (0, 0.75 and 1.0 are shown in the figure in grey, blue and black respectively), and will make the curve approximate a line when set to 0 (grey), and approximate a curve that hugs the intersection of the lines that are defined by the end points locations and the slopes at the end of each curve segment (red lines). Although you do not need to set all of this information directly, for some of the curves it is useful to know that both the slope and the curviness parameter may need to be altered to achieve the desired shape. \image html fig_GeometryAddon_quinticCornerSections.png Computational Cost Details All computational costs assume the following operation costs: \verbatim Operation Type : #flops *,+,-,=,Boolean Op : 1 / : 10 sqrt: 20 trig: 40 \endverbatim These relative weightings will vary processor to processor, and so any of the quoted computational costs are approximate. RBDL Port Notes The port of this code from OpenSim has been accompanied by a few changes: 1. The 'calcIntegral' method has been removed. Why? This function relied on having access to a variable-step error controlled integrator. There is no such integrator built into RBDL. Rather than add a dependency (by using Boost perhaps) this functionality has been removed. 2. The function name .printMuscleCurveToFile(...) has been changed to .printCurveToFile(). @author Matt Millard @version 0.0 */ namespace RigidBodyDynamics { namespace Addons { namespace Muscle{ class MuscleFunctionFactory { public: // friend class SmoothSegmentedFunction; /** This is a function that will produce a C2 (continuous to the second derivative) active force length curve. @param lce0 Normalized fiber length at the left-most shoulder of the active force-length curve. The value of the active force length curve for lce < lce0 will be equal to the value set in shoulderVal. Normally lce0 is approximately 0.5 @param lce1 Normalized fiber length at the transition point between the ascending limb and the plateau region of the active force length curve. @param lce2 Normalized fiber length at the maximum active force length curve value of 1. Normally lce2 is by definition 1. @param lce3 Normalized fiber length of the at the right most shoulder of the active-force length curve. The value of the active force length curve for lce > lce2 will be equal to the value of shoulderVal. Normally lce3 is approximately 1.5 @param minActiveForceLengthValue The minimum value of the active force length curve. A physiological non-equibrium muscle model would have this value set to 0. An equilibrium muscle model would have a non-zero lower bound on this value of 0.1 typically. shoulderVal must be greater than, or equal to 0. @param plateauSlope The slope of the plateau of the active force length curve between lce1 and lce2. This parameter can vary depending on the muscle model, but a value of 0.8616 is a good place to start. @param curviness The dimensionless 'curviness' parameter that can vary between 0 (a line) to 1 (a smooth, but sharply bent elbow). A value of 0 will yield an active force length curve that is composed of slightly curved line segments. A value of 1 will yield an active force length curve that is smoothly rounded. @param curveName The name of the muscle this curve applies to. This curve name should have the name of the muscle and the curve in it (e.g. "bicep_fiberActiveForceLengthCurve") sothat if this curve ever causes an exception, a userfriendly error message can be displayed to the end user to help them debug their model. @param smoothSegmentedFunctionToUpdate A SmoothSegmentedFunction object that will be erased and filled with the coefficients that are defined by this curve. \b aborts \b if these conditions aren't met -0 < lce0 < lce1 < lce2 < lce3 -shoulderVal >= 0 -0 <= plateauSlope < (1/(lce3-lce2)) -0 <= curviness <= 1 \image html fig_MuscleAddon_MuscleFunctionFactory_falCurve.png Conditions: Computational Costs \verbatim ~20,500 flops \endverbatim Example: @code double lce0 = 0.5; double lce1 = 0.75; double lce2 = 1; double lce3 = 1.5; double shoulderVal = 0.1; double plateauSlope = 0.75; double curviness = 0.9; SmoothSegmentedFunction fiberfalCurve = SmoothSegmentedFunction(); MuscleFunctionFactory:: createFiberActiveForceLengthCurve(lce0, lce1, lce2, lce3, shoulderVal, plateauSlope, curviness,"test", fiberfalCurve); fiberfalCurve.printCurveToFile(); @endcode */ static void createFiberActiveForceLengthCurve( double lce0, double lce1, double lce2, double lce3, double minActiveForceLengthValue, double plateauSlope, double curviness, const std::string& curveName, RigidBodyDynamics::Addons::Geometry ::SmoothSegmentedFunction& smoothSegmentedFunctionToUpdate); /** This function will generate a C2 continous (continuous to the second derivative) force velocity curve of a single muscle fiber. The main function of this element is to model the amount the force enhancement or attenuation that is associated with contracting at a particular velocity. @param fmaxE The normalized maximum force the fiber can generate when is being stretched. This value is reported to range between 1.1 and 1.8 in the literature, though all values are above 1. @param dydxC The slope of the fv(dlce(t)/dt) curve at the maximum normalized concentric contraction velocity. Although physiologically the value of dydxC at the maximum concentric contracton velocity is by definition 0, a value of 0 is often used. If you are using an equilbrium type model this term must be positive and greater than zero so that the fv curve can be inverted.

Minimum Value: 0 Maximum Value: dydxC < 1

@param dydxNearC The slope of the force velocity curve as it approaches the maximum concentric (shortening) contraction velocity.

Minimum Value: > dydxC Maximum Value: dydxNearC < 1

@param dydxIso The slope of the fv curve when dlce(t)/dt = 0.

Minimim Value: dydxIso > 1.0 Maximum Value: dydxIso < Inf @param dydxE The analogous term of dydxC parameter but for the eccentric portion of the force-velocity curve. As with the dydxC term, the physiologically accurate value for this parameter is 0, though a value of 0 is rarely used in muscle models. If you are using an equilbrium type model this term must be positive and greater than zero so that the fv curve can be inverted.

Minimum Value: 0 Maximum Value: dydxC < (fmaxE-1).

As with the dydxC term, the size of this term also affects the stiffness of the integration problem for equilibrium-type muscle models: the closer to zero this term is, the stiffer the model will be (but only when (dlce(t)/dt)/vmax approaches 1. @param dydxNearE The slope of the force velocity curve as it approaches the maximum eccentric (lengthening) contraction velocity.

Minimum Value: > dydxE Maximum Value: dydxNearE < (fmaxE-1)

@param concCurviness The dimensionless 'curviness' parameter that can vary between 0 (a line) to 1 (a smooth, but sharply bent elbow). This parameter affects only the concentric side of the fv curve. @param eccCurviness The dimensionless 'curviness' parameter that can vary between 0 (a line) to 1 (a smooth, but sharply bent elbow). This parameter affects only the eccentric side of the fv curve. @param curveName The name of the muscle this curve applies to. This curve name should have the name of the muscle and the curve in it (e.g. "bicep_fiberForceVelocityCurve") sothat if this curve ever causes an exception, a userfriendly error message can be displayed to the end user to help them debug their model. @param smoothSegmentedFunctionToUpdate A SmoothSegmentedFunction object that will be erased and filled with the coefficients that are defined by this curve. \b aborts \b unless these conditions are met -0 <= dydxC < 1 -dydxC < dydxNearC < 1 -1 < dydxIso -dydxE < (fmaxE-1) -dydxE < dydxNearC < (fmaxE-1) -0<= concCurviness <=0 -0 <= eccCurviness <= 0 \image html fig_MuscleAddon_MuscleFunctionFactory_fvCurve.png Computational Costs \verbatim ~8,200 flops \endverbatim Example: @code double fmaxE = 1.8; double dydxC = 0.1; double dydxNearC = 0.25; double dydxE = 0.1; double dydxNearE = 0.15; double dydxIso= 5; double concCurviness = 0.1; double eccCurviness = 0.75; SmoothSegmentedFunction fiberFVCurve = SmoothSegmentedFunction(); MuscleFunctionFactory:: createFiberForceVelocityCurve(fmaxE, dydxC, dydxNearC, dydxIso, dydxE, dydxNearE, concCurviness, eccCurviness,"test", fiberFVCurve); fiberFVCurve.printCurveToFile(); @endcode */ static void createFiberForceVelocityCurve( double fmaxE, double dydxC, double dydxNearC, double dydxIso, double dydxE, double dydxNearE, double concCurviness, double eccCurviness, const std::string& curveName, RigidBodyDynamics::Addons::Geometry:: SmoothSegmentedFunction& smoothSegmentedFunctionToUpdate); /** This function will generate a C2 continuous (continuous to the 2nd derivative) inverse curve that the function createFiberForceVelocityCurve generates. The inverse force velocity curve is required by every equilibrium muscle model in order to compute the derivative of fiber velocity. To generate the inverse force velocity curve simply call this function with EXACTLY the same parameter values that you used to generate the force velocity curve. See the parameter descriptions for createFiberForceVelocityCurve, as the parameters for the inverse function are identical. The curve name should be different, however, because this is an inverse curve (e.g. "bicep_fiberForceVelocityInverseCurve") \image html fig_MuscleAddon_MuscleFunctionFactory_fvInvCurve.png */ static void createFiberForceVelocityInverseCurve( double fmaxE, double dydxC, double dydxNearC, double dydxIso, double dydxE, double dydxNearE, double concCurviness, double eccCurviness, const std::string& muscleName, RigidBodyDynamics::Addons::Geometry:: SmoothSegmentedFunction& smoothSegmentedFunctionToUpdate); /** This element will generate a C2 continuous (continuous to the 2nd derivative) compressive force profile curve as a function of pennation. A muscle model with this element usually places this element parallel to the fiber.The main function of this element is to prevent the fiber from achieving a pennation angle of pi/2 radians. This type of element is necessary for a parallelogram pennated equilibrium muscle models because without it, the muscle model can deform to the point where a pennation angle of pi/2 radians is reached, which causes a singularity in the model. @param phi0 The pennation angle at which the compressive force element starts to engage . When the pennation angle is greater than phi0, the compressive element is generating a force. When the pennation angle is less than phi0, the compressive element generates no force. @param kiso This is the maximum stiffness of the compressive element, which occurs when the fiber is pennated by 90 degrees @param curviness The dimensionless 'curviness' parameter that can vary between 0 (a line) to 1 (a smooth, but sharply bent elbow) @param curveName The name of the muscle this curve applies to. This curve name should have the name of the muscle and the curve in it (e.g. "bicep_fiberCompressiveForcePennationCurve") sothat if this curve ever causes an exception, a userfriendly error message can be displayed to the end user to help them debug their model. @param smoothSegmentedFunctionToUpdate A SmoothSegmentedFunction object that will be erased and filled with the coefficients that are defined by this curve. \b aborts \b unless the following conditions are met -0 < phi0 < SimTK::Pi/2 -kiso > 1/(SimTK::Pi/2-phi0) -0 <= curviness <= 1 \image html fig_MuscleAddon_MuscleFunctionFactory_fcphiCurve.png Computational Costs \verbatim ~4,100 flops \endverbatim Example: @code double phi0 = (SimTK::Pi/2)*(8.0/9.0); double kiso = 8.389863790885878; double c = 0.0; SmoothSegmentedFunction fiberCEPhiCurve = SmoothSegmentedFunction(); MuscleFunctionFactory:: createFiberCompressiveForcePennationCurve(phi0,kiso,c,"test",fiberCEPhiCurve); fiberCEPhiCurve.printCurveToFile(); @endcode */ static void createFiberCompressiveForcePennationCurve( double phi0, double kiso, double curviness, const std::string& curveName, RigidBodyDynamics::Addons::Geometry:: SmoothSegmentedFunction& smoothSegmentedFunctionToUpdate); /** This element will generate a C2 continuous (continuous to the 2nd derivative) compressive force profile curve as a function of cos(pennation). A muscle model with this element usually places this element in line with the tendon. The main function of this element is to prevent the fiber from achieving a pennation angle of pi/2 radians. This type of element is necessary for a parallelogram pennated muscle models because without it, the muscle model can deform to the point where a pennation angle of pi/2 radians is reached, which causes a singularity in the model. @param cosPhi0 The cosine of the pennation angle at which the compressive force element starts to engage. When the cos of the pennation angle is greater than cosPhi0, the compressive element generates no force. When cos of the pennation angle is less than cosPhi0, the compressive element generates a compressive force. @param kiso This is the maximum stiffness of the compressive element, which occurs when cosPhi is zero. This parameter must be negative cos @param curviness The dimensionless 'curviness' parameter that can vary between 0 (a line) to 1 (a smooth, but sharply bent elbow) @param curveName The name of the muscle this curve applies to. This curve name should have the name of the muscle and the curve in it (e.g. "bicep_fiberCompressiveForceCosPennationCurve") sothat if this curve ever causes an exception, a userfriendly error message can be displayed to the end user to help them debug their model. @param smoothSegmentedFunctionToUpdate A SmoothSegmentedFunction object that will be erased and filled with the coefficients that are defined by this curve. \b aborts \b unless the following conditions are met: -0 < cosPhi0 -kiso > 1/(cosPhi0) -0 <= curviness <= 1 \image html fig_MuscleAddon_MuscleFunctionFactory_fcCosPhiCurve.png Computational Costs \verbatim ~4,100 flops \endverbatim Example: @code double cosPhi0 = cos( (80.0/90.0)*SimTK::Pi/2); double kiso = -1.2/(cosPhi0); double c = 0.5; SmoothSegmentedFunction fiberCECosPhiCurve = MuscleFunctionFactory:: createFiberCompressiveForceCosPennationCurve(cosPhi0,kiso,c,"test"); fiberCEPhiCurve.printCurveToFile(); @endcode */ static void createFiberCompressiveForceCosPennationCurve( double cosPhi0, double kiso, double curviness, const std::string& curveName, RigidBodyDynamics::Addons::Geometry:: SmoothSegmentedFunction& smoothSegmentedFunctionToUpdate); /** This element will generate a C2 continous (continuous to the second derivative) curve that models a compressive force profile that is a function of fiber length. The main function of this element is to prevent the fiber from achieving an unrealistically short length. This type of element is necessary for equilibrium-type muscle models because of the editing that is done to the active force length curve that endows an equilibrium model fiber with the ability to to generate force when a physiological fiber cannot. @param l0 The normalized fiber length at which the compressive element starts to engage. When the fiber is shorter than l0, the compressive element is generating a force. When the fiber length is longer than l0, the compressive element generates no force. @param kiso This is the maximum stiffness of the compressive element, which occurs when the fiber has a length of 0, under a load of 1 maximum isometric unit of force. @param curviness The dimensionless 'curviness' parameter that can vary between 0 (a line) to 1 (a smooth, but sharply bent elbow) @param curveName The name of the muscle this curve applies to. This curve name should have the name of the muscle and the curve in it (e.g. "bicep_fiberCompressiveForceLengthCurve") sothat if this curve ever causes an exception, a userfriendly error message can be displayed to the end user to help them debug their model. @param smoothSegmentedFunctionToUpdate A SmoothSegmentedFunction object that will be erased and filled with the coefficients that are defined by this curve. \b aborts \b unless the following conditions are met -e0 > 0 -kiso > 1/(e0) -0 <= curviness <= 1 \image html fig_MuscleAddon_MuscleFunctionFactory_fpeCurve.png Computational Costs \verbatim ~4,100 flops \endverbatim Example: @code double lmax = 0.6; double kiso = -8.389863790885878; double c = 0.1;//0.0; SmoothSegmentedFunction fiberCECurve = MuscleFunctionFactory:: createFiberCompressiveForceLengthCurve(lmax,kiso,c,"test"); fiberCECurve.printCurveToFile(); @endcode */ static void createFiberCompressiveForceLengthCurve( double l0, double kiso, double curviness, const std::string& curveName, RigidBodyDynamics::Addons::Geometry:: SmoothSegmentedFunction& smoothSegmentedFunctionToUpdate); /** This function will generate a C2 continuous curve that fits a fiber's tensile force length curve. @param eZero The fiber strain at which the fiber begins to develop force. Thus an e0 of 0.0 means that the fiber will start to develop passive force when it has a normalized length of 1.0. Note that e0 can be postive or negative. @param eIso The fiber strain at which the fiber develops 1 unit of normalized force (1 maximum isometric force). Note that the '1' is left off. Thus an e0 of 0.6 means that the fiber will develop an 1 normalized force unit when it is strained by 60% of its resting length, or to a normalized length of 1.6 @param kLow The normalized stiffness (or slope) of the fiber curve close to the location where the force-length curve approaches a normalized force of 0. This is usually chosen to be a small, but non-zero fraction of kIso (kLow = 0.025 kIso is typical). @param kIso The normalized stiffness (or slope) of the fiber curve when the fiber is strained by eIso (or has a length of 1+eIso) under a load of 1 maximum isometric unit of force. @param curviness The dimensionless 'curviness' parameter that can vary between 0 (a line) to 1 (a smooth, but sharply bent elbow) @param curveName The name of the muscle this curve applies to. This curve name should have the name of the muscle and the curve in it (e.g. "bicep_fiberForceLengthCurve") sothat if this curve ever causes an exception, a userfriendly error message can be displayed to the end user to help them debug their model. @param smoothSegmentedFunctionToUpdate A SmoothSegmentedFunction object that will be erased and filled with the coefficients that are defined by this curve. \b aborts \b unless the following conditions are met -eIso > eZero -kIso > 1/(eIso-eZero) -0 < kLow < kIso -0 <= curviness <= 1 \image html fig_MuscleAddon_MuscleFunctionFactory_fcLengthCurve.png Computational Costs \verbatim ~4,100 flops \endverbatim Example: @code double eIso = 0.6; double eZero = 0.0; double kIso = 4.0/(eIso-eZero); double kNearZero = 0.025*kIso double c = 0.5; SmoothSegmentedFunction fiberFLCurve = MuscleFunctionFactory:: createFiberForceLengthCurve(eZero, eIso, kLow, kIso, c,"test"); fiberFLCurve.printCurveToFile(); @endcode */ static void createFiberForceLengthCurve( double eZero, double eIso, double kLow, double kIso, double curviness, const std::string& curveName, RigidBodyDynamics::Addons::Geometry:: SmoothSegmentedFunction& smoothSegmentedFunctionToUpdate); /** Will generate a C2 continous (continuous to the second derivative) curve in a MuscleFunctionObject object that fits a tendon's tensile force length curve. @param eIso The tendon strain at which the tendon develops 1 unit of normalized force (1 maximum isometric force). Note that the'1' is left off. Thus an e0 of 0.04 means that the tendon will develop an 1 normalized force unit when it is strained by 4% of its resting length, at a normalized length of 1.04 @param kIso The normalized stiffness (or slope) of the tendon curve when the tendon is strained by e0 (or has a length of 1+e0) under a load of 1 maximum isometric unit of force. @param fToe The normalized force at which the tendon smoothly transitions from the curved low stiffness region to the linear stiffness region. @param curviness The dimensionless 'curviness' parameter that can vary between 0 (a line) to 1 (a smooth, but sharply bent elbow) @param curveName The name of the muscle this curve applies to. This curve name should have the name of the muscle and the curve in it (e.g. "bicep_tendonForceLengthCurve") sothat if this curve ever causes an exception, a userfriendly error message can be displayed to the end user to help them debug their model. @param smoothSegmentedFunctionToUpdate A SmoothSegmentedFunction object that will be erased and filled with the coefficients that are defined by this curve. \b aborts \b unless the following conditions are met: -0 < fToe < 1 -e0 > 0 -kiso > 1/e0 -0 <= curviness <= 1 \image html fig_MuscleAddon_MuscleFunctionFactory_fseCurve.png Computational Costs \verbatim ~4,100 flops \endverbatim Example: @code double e0 = 0.04; double kiso = 42.79679348815859; double fToe = 1.0/3.0 double c = 0.75; SmoothSegmentedFunction* tendonCurve = MuscleFunctionFactory:: createTendonForceLengthCurve( e0,kiso,fToe,c,"test"); tendonCurve.printCurveToFile(); @endcode */ static void createTendonForceLengthCurve(double eIso, double kIso, double fToe, double curviness, const std::string& curveName, RigidBodyDynamics::Addons::Geometry:: SmoothSegmentedFunction& smoothSegmentedFunctionToUpdate); }; } } } #endif //MUSCLEFUNCTIONFACTORY_H_